01321nas a2200289 4500000000100000008004100001260001300042653001000055653000900065653001100074653001700085653001100102653001200113653000900125653001600134100001500150700001300165700001300178700001700191700001400208245005500222300001000277490000700287050003200294520069100326022001401017 1979 d c1979 Apr10aAdult10aAged10aFemale10aFibrinolysis10aHumans10aleprosy10aMale10aMiddle Aged1 aSharda D P1 aParvez M1 aJain A K1 aBhargava N C1 aMisra S N00aA study of serum fibrinolytic activity in leprosy. a203-80 v51 aInfolep Library - available3 a
Fibrinolytic activity was studied in 50 patients of leprosy and 30 healthy individuals who served as control. Fibrinolytic activity was determined by measuring euglobulin lysis. No significant alteration in fibrinolytic activity was observed in patients with non-lepromatous leprosy, the levels being approximately similar to control group. However, fibrinolytic activity was found to be significantly decreased in patients of lepromatous leprosy and lepra reaction group. The observed decrease in fibrinolytic activity can be explained on the basis of presence of tissue destruction and vasculitis seen in leprosy more so in patients with lepromatous leprosy and lepra reaction.
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