01407nas a2200277   4500000000100000008004100001260001300042653001700055653001300072653002700085653002500112653003300137653001100170653001200181653001900193100002000212700001800232700001400250700001800264700002000282245016200302300000900464490000700473520063500480022001401115       1979                            d  c1979 Mar10aBlood Donors10aEpitopes10aHepatitis B Antibodies10aHepatitis B Antigens10aHepatitis B Surface Antigens10aHumans10aleprosy10aLiver Diseases1 aThyagarajan S P1 aSubramaniam S1 aSolomon S1 aPanchanadam M1 aMadanagopalan N00aAntigenic subtypes of HBsAg: their distribution and pattern of occurence among blood donors and patients with liver diseases and leprosy in Tamilnadu, India.  a62-60 v823 a<p>One hundred and seventy hepatitis B Surface antigen positive sera derived from blood donors, patients with liver diseases and leprosy were antigenically subtyped by Rheophoresis and 107 of them by agar-gel diffusion. For the first time in India HBsAg/adr as a predominant subtype (64.0%) is documented. Of the two methods adopted, Rheophoresis showed a greater sensitivity of typing, namely 82.3% in contrast to 39.2% only by agar-gel diffusion (p less than 0.001). Analysis of the Hepatitis Be antigen and antibody (anti HBe) positive sera for subtype predeliction revealed the same pattern as in HBe system negative sera.</p>  a0022-5304