01797nas a2200421   4500000000100000008004100001260000900042653001500051653001000066653001600076653003100092653001000123653002100133653002000154653001200174653001100186653001800197653001100215653002100226653001100247653001000258653001200268653000900280653001600289653002800305653002000333653001600353653001600369653002900385100001100414700001500425245013200440856008300572300001100655490000700666520068800673022001401361       1972                            d  c197210aAdolescent10aAdult10aAge Factors10aAntigen-Antibody Reactions10aChild10aChild, Preschool10aChronic Disease10aEcology10aFemale10aHelminthiasis10aHumans10aImmunoglobulin M10aInfant10aKenya10aleprosy10aMale10aMiddle Aged10aPopulation Surveillance10aschistosomiasis10aSex Factors10aTrypanosoma10aTrypanosomiasis, African1 aBinz G1 aWatson H J00aObservations on the patterns of blood IgM levels in the populations of endemic and nonendemic sleeping sickness areas in Kenya.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2480936/pdf/bullwho00186-0071.pdf  a757-670 v473 a<p>Increased levels of serum immunoglobulin M (IgM) may be related to a wide range of antigenic stimuli provided by a variety of infections to which people are repeatedly exposed. Most, if not all, of the natural antibodies against bacterial and cellular antigens have been found to belong to the IgM class. It is known that IgM levels in the blood increase in trypanosomiasis but it is not possible to demonstrate trypanosomes in all persons who show raised IgM levels in serological surveys in an endemic sleeping sickness area. Although survey data are limited, this paper discusses the usefulness of IgM tests as an aid to the detection of Trypanosoma rhodesiense infections.</p>  a0042-9686