01044nas a2200241   4500000000100000008004100001260000900042653001200051653001600063653001100079653003000090653002300120653001200143653000900155653001300164653001600177245005100193856008300244300001100327490000700338520044300345022001400788       1973                            d  c197310aAnimals10aBCG Vaccine10aHumans10aHypersensitivity, Delayed10aImmunity, Cellular10aleprosy10aMice10aResearch10aVaccination00aImmunological problems in leprosy research. 2.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481108/pdf/bullwho00177-0098.pdf  a483-940 v483 a<p>Part 2 of this Memorandum covers possible mechanisms of altered immune response in leprosy (including a tentative scheme to explain the possible genesis of the lepromatous lesion); genetic, nutritional, and hormonal factors; the possibility of vaccination; attempts at immunotherapy; and areas in which further research is needed. A detailed protocol for evaluating the effect of transfer factor in leprosy is included as an annex.</p>  a0042-9686