00973nas a2200241 4500000000100000008004100001260001300042653001000055653001200065653001100077653001100088653001200099653000900111653001300120100001900133700001800152245005800170300000900228490000700237050003200244520044100276022001400717 1979 d c1979 Jan10aAdult10aDapsone10aFemale10aHumans10aleprosy10aMale10aRifampin1 aBalakrishnan S1 aSheshadri P S00aInfluence of rifampicin on D.D.S. excretion in urine. a54-90 v51 aInfolep Library - available3 a

The plasma half-lives and urinary excretion levels of DDS were compared before and during concurrent administration of Rifampicin in 23 cases of active lepromatous leprosy. The plasma half-life of DDS was found to be slightly less during Rifampicin administration. The urinary excretion of DDS was found to be consistently enhanced in all the cases, particularly duotal duration of Rifampicin therapy. The findings are discussed.

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