02598nas a2200385 4500000000100000008004100001260001300042653001500055653001000070653002900080653001100109653001100120653002200131653001100153653001200164653002400176653002500200653000900225653001600234653001300250653001500263653001500278653001700293100001300310700001400323700001500337700001300352700001700365245010800382300001200490490000700502050001600509520167300525022001402198 2001 d c2001 Dec10aAdolescent10aAdult10aAnti-Inflammatory Agents10aBrazil10aFemale10aFollow-Up Studies10aHumans10aleprosy10aLeprosy, Borderline10aLeprosy, lepromatous10aMale10aMiddle Aged10aNeuritis10aPrednisone10aRecurrence10aTime Factors1 aDebray M1 aHanslik T1 aAvansi M A1 aPabion B1 aLortholary O00a[Surgical decompression treatment of leprous neuritis at the Bom-Pastor Hospital (Brazilian Amazonia)]. a1188-950 v22 aDEBRAY 20013 a

PURPOSE: Only leprosy resource centres undertake surgery for neuritis. Patients' accessibility to this surgical procedure is poor because these centres are often far from their homes. The aim of our work is to study the feasibility of neuritis surgery in the field.

METHODS: A surgeon trained in this surgery was recruited by Bom-Pastor hospital in Brazilian Amazonia, which is located 400 km away from the leprosy resource centre. Patients operated from May 1996 to December 1997 were enrolled in this retrospective study.

RESULTS: A total of 45 operations were carried out during 17 procedures on 13 patients, among which 12 were multibacillary cases. The decompression surgery was performed with a median delay of 1 year after leprosy diagnosis and 3.5 months after the neuritis diagnosis. Among 17 operations, 14 were performed for painful neuritis of recent onset unsuccessfully treated with corticoids or recurring during the month after corticoids were withdrawn. The other three operations were performed for long-standing neuritis with paralysis and deformity. Pain was relieved in all the cases of recent neuritis, except for one patient who suffered from a serious steroid-dependant erythema nodosum leprosum. An improvement of motor function was observed in one out of three patients with long-standing neuritis. Adverse effects were few: a scar infection with a rapid recovery and a keloid scar. Two neurites recurred 2 and 10 months after the surgery.

CONCLUSIONS: In an endemic leprosy region, field access to surgery for neuritis appears to prove real progress in the management of leprosy neuritis.

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