01708nas a2200289 4500000000100000008004100001260000900042653001000051653001600061653001100077653001300088653001200101653001200113653001500125653001700140100001700157700001800174700001200192700001300204700001600217245010500233856008300338300001000421490000700431520096600438022001401404 1973 d c197310aAdult10aAge Factors10aHumans10aLepromin10aleprosy10aMyanmar10aSkin Tests10aTime Factors1 aBechelli L M1 aGarbajosa P G1 aGyi M M1 aWalter J1 aTamondong C00aLate lepromin reaction in untreated patients with indeterminate leprosy under 21 years old in Burma. uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481033/pdf/bullwho00174-0118.pdf a113-60 v483 a

Studies on lepromin reactivity in indeterminate (I) leprosy have usually been carried out among patients in whom the disease appeared 1 or more years before testing. This may result in misleading findings because a high proportion of patients, probably those showing moderate or strong lepromin reactions, seem to progress to the tuberculoid pole of leprosy in a relatively short time (<1 year), and in many the lesions heal spontaneously. The object of the present study was to determine the frequency and intensity of late lepromin reactions (macroscopic readings) in untreated I patients aged under 21 years who had had the disease for less than 1 year. Of 209 patients tested with lepromin containing 160 x 10(6) bacilli/ml only a small proportion ( not equal 7%) showed a negative or doubtful lepromin reaction, while 61.5% were 2+ and 3+ reactors. These findings indicate that a favourable outcome may be expected in most I cases in the trial area.

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