02494nas a2200481   4500000000100000008004100001260001300042653001500055653001000070653000900080653001000089653002200099653001000121653002100131653001100152653002000163653002000183653001100203653003000214653002800244653001100272653002300283653001200306653002400318653002500342653002500367653000900392653001600401653001300417653001600430653002600446653001600472100001300488700001500501700001700516700001400533245006600547300001200613490000700625050001600632520135000648022001401998       2004                            d  c2004 Nov10aAdolescent10aAdult10aAged10aChild10aDrug Combinations10aEdema10aErythema Nodosum10aFemale10aFoot Dermatoses10aHand Dermatoses10aHumans10aHypersensitivity, Delayed10aImmune Complex Diseases10aIritis10aLeprostatic Agents10aleprosy10aLeprosy, Borderline10aLeprosy, lepromatous10aLeprosy, Tuberculoid10aMale10aMiddle Aged10aNeuritis10aPeriostitis10aRetrospective Studies10aSex Factors1 aSharma N1 aKoranne RV1 aMendiratta V1 aSharma RC00aA study of leprosy reactions in a tertiary hospital in Delhi.  a898-9030 v31  aSHARMA 20043 a<p>A retrospective study of 531 leprosy patients was undertaken to study the profile of reactions in the post Multi-Drug-Therapy period in a tertiary hospital in Delhi. BT was the most common group. The prevalence of reactions was found to be 8.09% for the Type 1 and 4.70% for the Type 2 reactions for a male:female ratio of 2.2. The Type 1 reaction was most frequently observed in the BB group followed by BL, BT and LL groups respectively. More than half of the patients had reactions at the time of presentation. In only 39.8% of the patients did reaction follow Multi-Drug-Therapy. In 4.5% of the patients with Type 1 reactions (T1R), concomitant infections were noted. The most common presentation of T1R was cutaneous lesions (74.41%) followed by cutaneous lesions and neuritis (53.6%), neuritis alone (12.1%), and only edema of hands and feet (7.31%) respectively. The Type 2 reactions (T2R) presented chiefly as papulo-nodular (92%) lesions followed by pustulonecrotic (8%) lesions. Associated neuritis was found in 40% and periosteitis and iritis in 8% and 4%, respectively. In 8.6% of the patients with T2R, precipitating factors could be observed. The prevalence of deformities in patients with reaction was 25%, and was more common in females. Deformities were observed in 23.25% of the T1R patients and 28% of the T2R patients.</p>  a0385-2407