01061nas a2200241 4500000000100000008004100001260001300042653001200055653001600067653002000083653001200103653000900115653003100124653001900155100001600174700001600190700001600206245014600222300001000368490000700378520042000385022001400805 1977 d c1977 Mar10aAnimals10aBCG Vaccine10aCross Reactions10aleprosy10aMice10aMycobacterium tuberculosis10aRNA, Bacterial1 aShepard C C1 aYoumans A Y1 aYoumans G P00aLack of protection afforded by ribonucleic acid preparations from Mycobacterium tuberculosis against Mycobacterium leprae infections in mice. a733-60 v153 a

Mycobacterial ribonucleic acid preparations from H37Ra, an attenuated strain of Mycobacterium tuberculosis, provide their usual marked protection against M. tuberculosis challenge; however, they provided no protection against Mycobacterium leprae challenge. Suspensions of intact H37Ra were not effective against M. leprae. Suspensions of BCG gave their usual distinct protection against M. leprae challenge.

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