01411nas a2200277   4500000000100000008004100001260001600042653001200058653001500070653001200085653003000097653001100127653001400138653001200152653000900164653002300173653001800196653001800214653001300232100001600245245006600261300001100327490000800338520077300346022001401119       1977                            d  c1977 Sep 0210aAnimals10aArmadillos10aDapsone10aDrug Therapy, Combination10aHumans10aIsoniazid10aleprosy10aMice10aModels, Biological10aMycobacterium10aProthionamide10aRifampin1 aFreerksen E00a[Research in the campaign against leprosy (author's transl)].  a1115-80 v1193 a<p>"Leprosy Relief through Leprosy Research" means that the results of research are made available for curing and eradicating the disease. The "Marinum Model" and the "planter test in mice" are, along with determination of serum activity in healthy test subjects, part of a complex of experiments for the assessment of the therapeutic value of an antimycobacterial substance. This replaces the "controlled studies" which, in their proper form, are scarcely possible for leprosy. With the recently developed forms of combination therapy, the duration of leprosy treatment is reduced to a few years. Because of the relationship of Mycobacterium leprae to Mycobacterium tuberculosis, certain types of combination therapy can be used in both diseases at the same time.</p>  a0341-3098