01237nas a2200241 4500000000100000008004100001260001700042653001200059653001100071653003800082653001100120653001200131653000900143100001300152700001900165700001200184245007200196300001100268490000700279050003200286520066300318022001400981 1985 d c1985 Apr-Jun10aDapsone10aFemale10aHemagglutination Inhibition Tests10aHumans10aleprosy10aMale1 aDe Wit M1 aBalakrishnan S1 aKumar A00aApplication of HI test for dapsone in urine under field conditions. a318-220 v57 aInfolep Library - available3 a
One hundred and two specimens of urine collected from leprosy patients attending the field clinics of Central Leprosy Teaching and Research Institute, Chingleput, Tamil Nadu, India, were screened for dapsone by the paper spot test and Haemagglutination Inhibition (HI) tests. A concordance of about 90% was observed between the two tests. Both tests showed their merits. The lower sensitivity of the spot test finds more cases of irregular compliance (1-2 days), whereas the higher sensitivity of the HI allows the demonstration of the intake of lower doses and the detection of those cases, who have grossly missed their tablets (longer than a week).
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