01211nas a2200325   4500000000100000008004100001260001300042653001600055653001100071653001100082653002400093653002200117653002100139653001600160653001400176653001600190100001300206700001700219700001300236700001300249700001500262700001500277700001500292700001200307245004100319300000800360490000800368520049500376022001400871       1986                            d  c1986 Jan10aClofazimine10aFemale10aHumans10aIntestinal Diseases10aIntestinal Mucosa10aIntestine, Small10aLymph Nodes10aMesentery10aMiddle Aged1 aJost J L1 aVenencie P Y1 aCortez A1 aOrieux G1 aDebbasch L1 aChomette G1 aPuissant A1 aVayre P00a[Enteropathy caused by clofazimine].  a7-90 v1233 a<p>A case of Clofazimine enteropathy is reported, diagnosed on the demonstration of red brown birefringent crystals in the small bowel mucosa and submucosa as well as in the mesenteric lymph nodes whereas the clinical and radiological signs appear to be non specific. After the withdrawal of the drug, a clear improvement of the symptoms was achieved only under a gluten free diet. The possibility of such accidents, sometimes lethal, suggests the restriction of clofazimine to leprosy.</p>  a0021-7697