01449nas a2200253 4500000000100000008004100001260001700042653002600059653003000085653003500115653001100150653001200161653002400173653001000197100001500207700001700222700001200239245008900251300001000340490000700350050003200357520079200389022001401181 1985 d c1985 Apr-Jun10aAntibodies, Bacterial10aBlood Specimen Collection10aFluorescent Antibody Technique10aHumans10aleprosy10aMycobacterium bovis10aPaper1 aBhatia V N1 aSudarsanam D1 aRoy R G00aUse of Whatman chromatography paper for serological studies in leprosy in the field. a341-50 v57 aInfolep Library - available3 a

Recently W.H.O. recommended further serological studies on leprosy using samples collected on filter paper strips. A study was therefore taken up at C.L.T. and R.I., Chengalpattu, to find out the relative efficiency of the serological tests conducted on sera and filter paper eluates. FLA-ABS and FA-BCG tests were carried out on 100 paired samples. With the former, exactly the same titres were obtained in 42% and with the latter in 52% cases. Most of the others showed positivity at one-dilution-low titres. In 6-8% cases only, the filter paper technique showed negativity. The correlation co-efficient was +0.87 with FLA-ABS and +0.85 with FA-BCG test. The filter paper technique was operationally more convenient and was acceptable without substantially loosing the efficacy.

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