01172nas a2200253 4500000000100000008004100001260001300042653001000055653001100065653001100076653001100087653001200098653000900110653002500119653001600144653002500160653001700185100001300202245011800215300001100333490000700344520055300351022001400904 1985 d c1985 Dec10aAdult10aBiopsy10aFemale10aHumans10aleprosy10aMale10aMicroscopy, Electron10aMiddle Aged10aMycobacterium leprae10aNasal Mucosa1 aHirata T00aElectron microscopic observations of acid-fast bacilli in nasal mucosal biopsies of lepromatous leprosy patients. a577-810 v533 a

The fine structure of acid-fast bacilli in nasal mucosal lepromas of lepromatous leprosy patients was studied in ultrathin sections by the electron microscope. The cell envelope of the bacilli was the main point of these observations. The electron microscopic examination of some of the bacilli revealed the envelope to be multilaminate. Some of the cellular matter was filled with an electron-less-dense, amorphous substance, surrounded with a membrane-like structure, and was adherent to the outermost layer of the bacillary cell envelope.

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