01379nas a2200277   4500000000100000008004100001260001700042653001200059653001200071653002000083653001500103653002600118653001600144653000900160100001600169700001200185700001100197700001600208700002000224245006600244300001000310490000700320050003200327520072800359022001401087       1985                            d  c1985 Jan-Mar10aAnimals10aleprosy10aLeukocyte Count10aLevamisole10aLymphocyte Activation10aLymphocytes10aMice1 aGanguly N K1 aKumar B1 aKaur S1 aVaishnavi C1 aChakravarti R N00aInfluence of levamisole on lymphocytes and M. leprae in mice.  a27-360 v57  aInfolep Library - available3 a<p>Normal uninfected (N) and M. leprae infected mice (NI) were given levamisole in the dose of 2.5 mg/kg body weight. The animals were observed over a period of nine months for bacillary load, T and B cell counts and blast transformation with PHA. Significant increase in B cell counts was observed in the levamisole treated normal (NL) compared to normal control (N) group. T cell counts and blast transformation, however, remained unaffected. However, T-cell counts and blast transformation improved significantly in the infected and levamisole treated (NIL) as compared to the infected group (NI) not given levamisole. Bacillary loads remained unaltered in both, the infected (NI) and levamisole treated (NIL) group.</p>  a0254-9395