01209nas a2200241   4500000000100000008004100001260001700042653001200059653001500071653001200086653001600098653002500114100001200139700001600151700001800167700001700185245005200202300000900254490000700263050003200270520065100302022001400953       1985                            d  c1985 Jan-Mar10aAnimals10aArmadillos10aleprosy10aMacrophages10aMicroscopy, Electron1 aJob C K1 aSanchez R M1 aMcCormick G T1 aHastings R C00aFirst lesion in experimental armadillo leprosy.  a71-70 v57  aInfolep Library - available3 a<p>Eighteen armadillos were infected intravenously with 10(8) M. leprae and 10 intracutaneously with 10(7) M. leprae. Among those which developed disseminated disease, a nodule at the site of inoculation was the first lesion noticed in 14 of the 16 infected intravenously and 4 of the 4 infected intradermally. It is possible that in human leprosy the first sign of infection is localized proliferation of M. leprae at the site of entry, and even nodule formation in lepromatous patients. It may be important to search for asymptomatic swelling or keloid-like lesions in skin or in nasal mucosa while screening a population for early leprosy.</p>  a0254-9395