01465nas a2200325   4500000000100000008004100001260001300042653001200055653001500067653001100082653001200093653001000105653001600115653001600131653000900147653002500156653001400181653001800195653000900213653001100222653001400233100001200247700001600259700001700275245006100292300001100353490000700364520075400371022001401125       1985                            d  c1985 Jan10aAnimals10aArmadillos10aFemale10aleprosy10aLiver10aLymph Nodes10aMacrophages10aMale10aMycobacterium leprae10aPregnancy10aSciatic Nerve10aSkin10aSpleen10aXenarthra1 aJob C K1 aSanchez R M1 aHastings R C00aManifestations of experimental leprosy in the armadillo.  a151-610 v343 a<p>Three experiments, using different routes and doses of infection, were conducted using 42 armadillos. Thirty-six of them developed generalized disease. There is no significant sex or age difference in susceptibility. Route and dose of infection make very little difference in the disease prevalence except that the intravenous administration of a large dose reduces the period of development of generalized disease. It is quite possible that in armadillos the resistance to the disease is partly genetic. Although a majority of the armadillos developed lepromatous disease, borderline leproma is fairly common. In skin nodules large colonies of extracellular bacilli are demonstrated. Bacilli are also demonstrated in liver parenchymal cells.</p>  a0002-9637