01043nas a2200277   4500000000100000008004100001260001300042653001100055653002300066653002500089653001100114653001200125653001600137653002600153653001600179653002500195653002500220653000900245100001700254700001500271245010400286300000900390490000700399520034500406022001400751       1985                            d  c1985 Mar10aBiopsy10aCell Communication10aCell Differentiation10aHumans10aleprosy10aLymphocytes10aMacrophage Activation10aMacrophages10aMicroscopy, Electron10aMycobacterium leprae10aSkin1 aBurchard G D1 aBierther M00aAn electron microscopic study on macrophages and lymphocytes in lepromatous and borderline leprosy.  a64-90 v533 a<p>We describe how macrophages are activated and phagocytose mycobacteria in lepromatous leprosy. The differentiation of macrophages into epithelioid cells and into giant cells in borderline leprosy is shown. Close apposition between macrophages and lymphocytes is seen in those areas where mycobacteria disintegrate inside macrophages.</p>  a0148-916X