01061nas a2200217 4500000000100000008004100001260001300042653002700055653001100082653001100093653001200104653000900116653002500125653001800150100001300168245008000181300001000261490000800271520055000279022001400829 1985 d c1985 Jun10aFatty Acids, Essential10aFemale10aHumans10aleprosy10aMale10aMycobacterium leprae10aPhospholipids1 aWright S00aEssential fatty acids in the plasma phospholipids of patients with leprosy. a673-70 v1123 a
Plasma phospholipid essential fatty acids were investigated in 40 patients with leprosy and 40 controls. A significant reduction in linoleic acid was found in the leprosy patients, with an increase in its metabolite dihomo-gamma-linolenic acid. No difference was found between patients with multibacillary and paucibacillary leprosy. Patients treated for less than 6 months were found to have low levels of linoleic acid and high levels of dihomo-gamma-linolenic and arachidonic acid compared with patients treated for more than 6 months.
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