01226nas a2200265 4500000000100000008004100001260001300042653002600055653002400081653002100105653001600126653001100142653001200153653002500165100001500190700001400205700001300219700001400232700001300246245013000259300001000389490000700399520054000406022001400946 1985 d c1985 Jun10aAntibodies, Bacterial10aAntigens, Bacterial10aErythema Nodosum10aGlycolipids10aHumans10aleprosy10aMycobacterium leprae1 aAndreoli A1 aBrett S J1 aDraper P1 aPayne S N1 aRook G A00aChanges in circulating antibody levels to the major phenolic glycolipid during erythema nodosum leprosum in leprosy patients. a211-70 v533 a

Circulating antibody levels to the phenolic glycolipid from Mycobacterium leprae and soluble M. leprae antigens were monitored before, during and following ENL episodes in 12 patients. It was observed that during ENL reaction, there was a fall in circulating antibody levels to the phenolic glycolipid but not to the soluble antigens from M. leprae. When the patients had recovered from their ENL reactions, the anti-glycolipid antibody levels usually increased again to levels similar to those observed before the ENL reaction.

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