01454nas a2200325   4500000000100000008004100001260001300042653001500055653001000070653002800080653001900108653002400127653001000151653002100161653001100182653001100193653001200204653000900216653002400225653002300249653002200272100002100294700002000315700002600335245010400361300001100465490000700476520063100483022001401114       1985                            d  c1985 Aug10aAdolescent10aAdult10aAntibodies, Antinuclear10aBlood Proteins10aBlood Sedimentation10aChild10aErythema Nodosum10aFemale10aHumans10aleprosy10aMale10aProspective Studies10aRheumatic Diseases10aRheumatoid Factor1 aChavez-Legaspi M1 aGomez-Vazquez A1 aGarcía-De La Torre I00aStudy of rheumatic manifestations and serologic abnormalities in patients with lepromatous leprosy.  a738-410 v123 a<p>We investigated the rheumatic and laboratory features associated with rheumatic syndromes in 32 patients with lepromatous leprosy. Twenty-seven (84%) developed a broad range of rheumatic manifestations, the most common being the presence of arthritis which was symmetric and polyarticular, resembling rheumatoid arthritis. The laboratory abnormalities included an elevated sedimentation rate in 32 cases (100%), a positive rheumatoid factor in 6 (18.7%), and antinuclear antibodies in one (3.1%). A careful history and the recognition of rheumatic manifestations will help in the identification of this type of leprosy.</p>  a0315-162X