01147nas a2200241   4500000000100000008004100001260001700042653001600059653001100075653002600086653001200112653002800124100001300152700001700165700001800182700001100200245012800211300001000339490000700349050003200356520050300388022001400891       1985                            d  c1985 Jan-Mar10aClofazimine10aHumans10aIntestinal Absorption10aleprosy10aMonitoring, Physiologic1 aMathur A1 aVenkatesan K1 aBharadwaj V P1 aRamu G00aEvaluation of effectiveness of clofazimine therapy. I. Monitoring of absorption of clofazimine from gastrointestinal tract.  a146-80 v57  aInfolep Library - available3 a<p>The quantity of clofazimine absorbed from the gastrointestinal tract when administered to lepromatous leprosy patients at varying single doses of 600 mg., 400 mg., 300 mg., and 100 mg. has been worked out by determining the amount of clofazimine present in total faecal excreta. Except in 100 mg. dose where the percentage absorption was 62.5 +/- 17 in all other case the values were around 45%. The efficacy of daily administration of 100 mg. clofazimine is discussed in this first article.</p>  a0254-9395