01874nas a2200301   4500000000100000008004100001260001700042653001500059653001000074653001200084653003300096653003000129653001100159653002200170653001100192653001200203653000900215653001300224100001300237700001100250700001700261245013700278300001200415490000700427050003200434520109200466022001401558       1985                            d  c1985 Jul-Sep10aAdolescent10aAdult10aDapsone10aDrug Administration Schedule10aDrug Therapy, Combination10aFemale10aFollow-Up Studies10aHumans10aleprosy10aMale10aRifampin1 aKatoch K1 aRamu G1 aRamanathan U00aChemotherapeutic trials with different regimens containing rifampicin in paucibacillary type of leprosy cases--a preliminary report.  a499-5060 v57  aInfolep Library - available3 a<p>Different regimens containing Rifampicin have been tried in treating paucibacillary leprosy patients. In our study we have studied three regimens. Regimen I consists of treating patients with Rifampicin 600 mg once a month for six months combined with Dapsone 100mg daily and treatment is stopped at six months. Regimen II is same as regimen I except that instead of stopping treatment at the end of six months the treatment was continued with dapsone 100 mg daily for another six months and treatment was stopped at one year. Regimen III is the same as recommended by I.A.L. in which treatment is started with Rifampicin 600 mg daily for seven days in the first month to be followed by Rifampicin 600 mg once a month for five more months. This is combined with dapsone 100mg daily for one year. Treatment in this group is also stopped at one year. Eighty one patients in Regimen I, thirty five patients in Regimen II and sixty three patients in Regimen III completed the six month treatment. It was found that the inactivation index in all the three regimens was nearly the same.</p>  a0254-9395