01254nas a2200241 4500000000100000008004100001260001700042653002000059653001100079653001200090653001900102653001800121100001500139700001500154700001900169700001400188245007700202300001000279490000700289050003200296520067000328022001400998 1985 d c1985 Jul-Sep10aCholinesterases10aHumans10aleprosy10aLiver Diseases10aSerum Albumin1 aBulakh P M1 aRanade S M1 aChandorkar A G1 aMuley P R00aCorrelation between serum choline esterase and serum albumin in leprosy. a524-80 v57 aInfolep Library - available3 a

The clinical material included 255 cases of leprosy consisting of Tuberculoid leprosy (74), Lepromatous leprosy (116), Lepromatous leprosy with lepra reaction. Liver biopsy could be performed on 50 cases of Lepromatous leprosy. Specific granulomatous changes and parenchymal cell damage were the significant findings. Serum choline esterase and serum albumin are synthesized in liver. Serum Choline esterase levels in the present study decreased abruptly with exacerbation of the disease but the serum albumin levels declined gradually and slowly. Possible hypothesis to explain the correlation and uneven fall in activity is discussed at the cellular level.

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