01391nas a2200277 4500000000100000008004100001260001700042653001500059653001000074653001100084653001800095653001200113653001000125653001900135653002200154100001400176700001300190700001400203700001500217245003000232300001100262490000700273050003200280520078700312022001401099 1986 d c1986 Apr-Jun10aAdolescent10aAdult10aHumans10aIris Diseases10aleprosy10aPupil10aUveal Diseases10aUveitis, Anterior1 aRohatgi J1 aShorey P1 aLamba P A1 aSehgal V N00aUveal changes in leprosy. a208-150 v58 aInfolep Library - available3 a

A total of 424 leprosy patients were screened for uveal involvement. Uveal changes were found in 11.2% of these patients. Uveal involvement was more common in patients with greater duration of the disease and in patients on irregular Dapsone therapy. Of the patients with uveal involvement 82% were lepromatous, 16% were borderline and 2% were of tuberculoid leprosy. Uveal changes in form of active iridocyclitis (21.3%), healed iridocyclitis (58.5%), iris atrophy (10.6%), iris pearls (7.4%), small irregular pupil (46.7%), pupil refractory to dilatation (56.3%) were seen. Posterior segment involvement was rare. Lepromatous and borderline leprosy patients with no clinical evidence of uveal involvement had decreased power of accommodation as compared to normal subjects.

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