01283nas a2200241   4500000000100000008004100001260001700042653001000059653001200069653001100081653001200092653000900104653004100113653003400154100001600188700001400204245004400218300001100262490000700273050003200280520071500312022001401027       1986                            d  c1986 Apr-Jun10aAdult10aDapsone10aHumans10aleprosy10aMale10aPanniculitis, Nodular Nonsuppurative10aSubstance Withdrawal Syndrome1 aUplekar M W1 aAntia N H00aDapsone dependent nodular panniculitis.  a286-900 v58  aInfolep Library - available3 a<p>A patient recorded to be suffering from tuberculoid leprosy since 1973 and on regular Dapsone monotherapy for about nine years developed asymmetrical, erythematous, subcutaneous, nodular swellings restricted chiefly to the extensor aspects of lower limbs two months after discontinuation of Dapsone therapy. During the course of Dapsone treatment, the patient had developed similar swellings twice previously each time when he stopped the drug for about a month. The swellings disappeared on commencement of Dapsone Treatment. This has been reconfirmed under our supervision. The biopsy of one of the lesions revealed panniculitis with vasculitis. The original diagnosis of leprosy was probably invalid.</p>  a0254-9395