01567nas a2200385 4500000000100000008004100001260001300042653001800055653001000073653000900083653001500092653001200107653001100119653001100130653003000141653001200171653000900183653001600192653002800208653001500236100001600251700001500267700001100282700001800293700001200311700001400323700001200337700001400349245003900363856004100402300001200443490000700455520070500462022001401167 1986 d c1986 Sep10aAcetaminophen10aAdult10aAged10aAnalgesics10aAspirin10aFemale10aHumans10aKidney Papillary Necrosis10aleprosy10aMale10aMiddle Aged10aNephritis, Interstitial10aPhenacetin1 aSegasothy M1 aMuhaya H M1 aMusa A1 aRajagopalan K1 aLim K J1 aFatimah Y1 aKamal A1 aAhmad K S00aAnalgesic use by leprosy patients. uhttp://ila.ilsl.br/pdfs/v54n3a06.pdf a399-4020 v543 a
We questioned 235 subjects with leprosy regarding the consumption of analgesic preparations, and 46 subjects (19.5%) admitted to having consumed more than 2 kg of analgesics; the main reason for consumption was neuritic pain. The commonly consumed analgesics are paracetamol (acetaminophen) and local proprietary compound analgesics containing aspirin, phenacetin, and caffeine. Intravenous urograms were done on 28 of the 46 subjects, but none showed evidence of renal papillary necrosis. The reasons for this lack of renal papillary necrosis are postulated. Excessive ingestion of analgesics may be a contributory factor in the development of interstitial nephritis in patients with leprosy.
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