01049nas a2200205   4500000000100000008004100001260001700042653001800059653001100077653002800088653001200116653002500128653000900153100001300162245014500175300001000320490000700330520049200337022001400829       1978                            d  c1978 Jul-Dec10aCell Membrane10aHumans10aIntracellular Membranes10aleprosy10aMycobacterium leprae10aSkin1 aHirata T00aElectron microscopic observations of intracytoplasmic membranous structures in Mycobacterium leprae by means of serial ultrathin sectioning.  a372-50 v463 a<p>The fine structures and interconnections between the cytoplasmic membrane and mesosomes of Mycobacterium leprae in human skin were studied in ultrathin sections. These intracellular membranous organelles were seen as laminated structures and as clusters of vesicles, which were trilaminar consisting of two electron-dense layers separated by an electron-transparent zone. The formation of mesosomes seems to be initiated by invagination and/or folding of the cytoplasmic membrane.</p>  a0148-916X