01227nas a2200289 4500000000100000008004100001260000900042653002900051653001600080653001200096653002000108653001100128653002300139653001200162653001600174653001900190653001500209653001300224653001700237100001400254700001400268245008000282300001000362490000800372520054300380022001400923 1979 d c197910aClinical Trials as Topic10aClofazimine10aDapsone10aDrug Evaluation10aHumans10aLeprostatic Agents10aleprosy10aNetherlands10aPhenylthiourea10aRecurrence10aRifampin10aTime Factors1 aFaber W R1 aLeiker DL00aEvaluation of treatment of lepromatous leprosy patients in the Netherlands. a46-540 v1583 a

The results of treatment of the group of leprosy patients at the lepromatous side of the leprosy spectrum registered at the Department of Dermatology of the University of Amsterdam in the years 1950-1976 were studied. The average duration of treatment to obtain bacteriologically negative skin biopsies in patients who were untreated at the time of registration, was 5 years. A substantial number of patients suffered a relapse; the main reasons for these relapses were discontinuation of treatment and DDS treatment in low dosage.

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