01309nas a2200265   4500000000100000008004100001260001300042653002900055653001200084653002400096653002200120653001100142653001200153653000900165653001300174100001600187700001100203700001600214245008900230300001100319490000700330050003200337520066000369022001401029       1978                            d  c1978 Jul10aClinical Trials as Topic10aDapsone10aDouble-Blind Method10aFollow-Up Studies10aHumans10aleprosy10aMale10aRifampin1 aGirdhar B K1 aRamu G1 aDesikan K V00aIntroductory rifampicin therapy in lepromatous leprosy: a six month follow-up study.  a363-700 v50  aInfolep Library - available3 a<p>A double-blind comparative trial of 300 mg of Rifampicin given daily as against 50 mg D.D.S. administered likewise for an initial period of 3 months has been undertaken on 24 untreated cases of lepromatous leprosy. All the patients have been followed up for 6 months. The results revealed that patients in the former group became non-infective, as concluded from M.I. and mouse foot-pad results, within 3-4 weeks and their nasal ulcers healed faster. Clinical improvement was slightly better in the former group while no bacteriological differences were noticed in the two groups. E.N.L. was milder and slightly less common in the Rifampicin group.</p>  a0024-1024