01777nas a2200337   4500000000100000008004100001260001300042653001500055653001000070653001600080653000900096653001500105653002900120653001600149653001200165653001100177653001100188653001200199653000900211653001600220653002500236653001300261653001600274653000900290653002400299245012000323300001100443490000700454520096400461022001401425       1978                            d  c1978 Sep10aAdolescent10aAdult10aAge Factors10aAged10aCell Count10aClinical Trials as Topic10aClofazimine10aDapsone10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aMycobacterium leprae10aRifampin10aSex Factors10aSkin10aStatistics as Topic00aA statistical analysis of two chemotherapy trials in lepromatous leprosy. II. Interactions among patient variables.  a1015-80 v273 a<p>Interrelationships among six patient characteristics recorded upon entry into the trial were analyzed for 67 patients with lepromatous and near-lepromatous leprosy admitted into two chemotherapy trials. Sex was found to be significantly associated with age and with the histopathologic classification; disproportionately large numbers of older patients and of patients classified as borderline-lepromatous (BL) were males. Classifications of the disease process by clinical and histopathologic criteria were closely associated, but many patients classified BL on histopathological grounds were classified fully lepromatous by the clinical criteria. Measurements of the number of Mycobacterium leprae in the patients made by three methods were also significantly correlated. No significant correlations were found between either classification of the disease process on the one hand, and any of the measurements of the numbers of organisms on the other.</p>  a0002-9637