01243nas a2200277 4500000000100000008004100001260001700042653001200059653002900071653002700100653002100127653001200148653000900160653001500169100001600184700001100200700001200211700001100223700001600234245010500250300001000355490000700365050003200372520054700404022001400951 1986 d c1986 Oct-Dec10aAnimals10aAntigen-Antibody Complex10aDisease Models, Animal10aImmune Tolerance10aleprosy10aMice10aThymectomy1 aVaishnavi C1 aKaur S1 aKumar B1 aKaur H1 aGanguly N K00aCirculating immune complexes in normal and immunosuppressed mice infected with Mycobacterium leprae. a522-90 v58 aInfolep Library - available3 a

Mycobacterium leprae infection was produced through the footpads in normal and immunosuppressed mice. Circulating immune complexes were detected by specific binding test and by conglutinin binding assay for specific and total immune complexes respectively in the sera of these mice during different periods of infection. Out of the total 30 samples tested from the infected groups, 3 were positive by specific binding test and 5 by conglutinin binding ELISA. The implications of the findings in relation to human leprosy are discussed.

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