01216nas a2200277 4500000000100000008004100001260001700042653001500059653001000074653001600084653001100100653001200111653000900123653001600132653001700148653001600165100001500181700001500196700001700211245004700228300001000275490000700285050003200292520060000324022001400924 1986 d c1986 Oct-Dec10aAdolescent10aAdult10aClofazimine10aHumans10aleprosy10aMale10aMiddle Aged10aPrednisolone10aThalidomide1 aParikh D A1 aGanapati R1 aRevankar C R00aThalidomide in leprosy--study of 94 cases. a560-60 v58 aInfolep Library - available3 a
Thalidomide has a beneficial effect on type II Lepra reaction especially chronic and recurrent reaction. It helps to minimise steroid dependency. Thalidomide was given to 94 cases of type II lepra reaction, who had not responded to steroids or had repeated reactions. This clinical data was analysed regarding clinical improvement, relapse of reaction, side effects of the drug, etc. The analysis showed that all the patients improved remarkably and steroids could be withdrawn. If the competence of staff using this drug is enhanced, morbidity due to leprosy can considerably be reduced.
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