01463nas a2200277   4500000000100000008004100001260001700042653001900059653002200078653003500100653002300135653002800158653001100186653001200197653001900209653001900228100001500247700001500262700001600277700001400293245006200307300001000369490000700379520078500386022001401171       1986                            d  c1986 Jan-Mar10aAutoantibodies10aDiabetes Mellitus10aFluorescent Antibody Technique10aHepatitis, Chronic10aHepatitis, Viral, Human10aHumans10aleprosy10aLiver Diseases10aMuscle, Smooth1 aVieira L M1 aVieira A R1 aAlvariz F G1 aSarno E N00a[Anti-smooth muscle antibodies in a hospital population].  a15-200 v233 a<p>A total of 139 sera being 60 patients with liver disease were tested for auto-antibodies. Twenty six of the 60 patients had active chronic hepatitis, 19 acute hepatitis, 3 cirrhosis, 3 hepatosplenic schistosomiasis mansoni, and 9 miscelaneous liver pathology. We found positivity for smooth muscle antibody in 26 cases: smooth muscle antibody-V in 15 cases, for smooth muscle antibody-T in 9, and for smooth muscle antibody-G in 10 other patients. Nine out of 10 patients with positive smooth muscle antibody-G had chronic active hepatitis and the remaining had cirrhosis. The other kinds of smooth muscle antibodies were irregularly distributed among the different hepatic disease studied. The higher levels of auto-antibodies were found mostly in chronic hepatic disease.</p>  a0004-2803