01124nas a2200277 4500000000100000008004100001260001700042653001200059653004100071653001100112653002100123653001200144653000900156653002500165653002500190100001600215700001600231700001200247700001100259245008700270300001100357490000700368050003200375520042500407022001400832 1986 d c1986 Jul-Sep10aAnimals10aAntibody-Dependent Cell Cytotoxicity10aHumans10aImmune Tolerance10aleprosy10aMice10aMice, Inbred Strains10aMycobacterium leprae1 aGanguly N K1 aVaishnavi C1 aKumar B1 aKaur S00aADCC function in Mycobacterium leprae inoculated normal and immunosuppressed mice. a377-810 v58 aInfolep Library - available3 a
Normal and immunosuppressed mice were inoculated with Mycobacterium leprae obtained from untreated lepromatous patients. Besides monitoring the AFB counts in the footpads at 3,6 and 9 months post inoculation, antibody dependent cellular cytotoxicity (ADCC) function was studied. The ADCC function seen to be largely unaltered in the M. leprae infected animals, comparable to the observation made in human leprosy.
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