01004nas a2200277   4500000000100000008004100001260001300042653001000055653001200065653001600077653001200093653003100105653001100136653001200147653000900159653000900168653002500177100001200202700001500214700001900229245007200248300001100320490000700331520037400338022001400712       1986                            d  c1986 Sep10aAdult10aAnimals10aClofazimine10aDapsone10aDrug Resistance, Microbial10aHumans10aleprosy10aMale10aMice10aMycobacterium leprae1 aKar H K1 aBhatia V N1 aHarikrishnan S00aCombined clofazimine- and dapsone-resistant leprosy. A case report.  a389-910 v543 a<p>A preliminary report is presented on the finding in a patient with lepromatous leprosy relapsing after maintaining clinical inactivity and bacterial negativity with dapsone monotherapy for a period of 23 years. Interestingly, Mycobacterium leprae from the fresh skin lesions revealed resistance to both clofazimine and dapsone by standard mouse foot pad testing.</p>  a0148-916X