01310nas a2200265   4500000000100000008004100001260001300042653001800055653002100073653001100094653002100105653002100126653002100147653001200168653002000180653001800200100001500218700001500233700001500248245004300263300001000306490000700316520070700323022001401030       1986                            d  c1986 May10aComplement C310aErythema Nodosum10aHumans10aImmunoglobulin A10aImmunoglobulin G10aImmunoglobulin M10aleprosy10aLeukocyte Count10aT-Lymphocytes1 aSehgal V N1 aGautam R K1 aSharma V K00aImmunoprofile of reactions in leprosy.  a240-40 v253 a<p>The immunologic profile during erythema nodosum leprosum (ENL) revealed increased percentage and absolute count of B-lymphocytes, in addition to considerably lowered levels of complement component C3. Serum immunoglobulins--IgG, IgA, and IgM--were significantly raised after subsidence of ENL, whereas upgrading reaction showed an increase of absolute count of total T lymphocytes and percentage and count of B-lymphocytes. In addition, a raised serum IgM level was noted after regression of ENL. Downgrading reaction demonstrated a decreased percentage of early T-lymphocytes and raised the absolute count of B-lymphocytes. Serum IgA levels were found to be increased after amelioration of ENL.</p>  a0011-9059