01298nas a2200253   4500000000100000008004100001260001700042653001000059653000900069653001100078653001100089653001200100653000900112653001500121653001600136653000900152100001200161245004700173300001000220490000700230050003200237520076100269022001401030       1987                            d  c1987 Oct-Dec10aAdult10aAged10aFemale10aHumans10aleprosy10aMale10aMast Cells10aMiddle Aged10aSkin1 aKumar R00aMast cells in histoid lepromatous lesions.  a390-20 v59  aInfolep Library - available3 a<p>Ten patients with histoid lesions among the lepromatous leprosy cases, of both sexes in the age group of 35-65 years, were included in this study. Skin biopsy from the nodule with surrounding healthy skin of histoid lesion was taken. The biopsies were fixed in susa solution and processed for light microscopy. 5-7 mu thick sections were cut and stained with haematoxylin and eosin, Toludine blue and Fite faraco. Observations were made on the dermis to locate the mast cells and bacilli. Proliferation of mast cells and their degranulation was seen in the histoid nodule as compared to surrounding normal healthy skin where the cells were mainly intact. The study further investigates the role of mast cells in the histopathogenesis of the disease.</p>  a0254-9395