01266nas a2200301 4500000000100000008004100001260000900042653002400051653003800075653001600113653001100129653002100140653001200161653002500173653002500198653002100223653002400244653002100268100001500289700001400304700001300318700001500331245011200346300001100458490000700469520047400476022001400950 1987 d c198710aAntigens, Bacterial10aEnzyme-Linked Immunosorbent Assay10aGlycolipids10aHumans10aImmunoglobulin M10aleprosy10aLongitudinal studies10aMycobacterium leprae10aPapua New Guinea10aProspective Studies10aRural Population1 aBaumgart K1 aBritton W1 aBasten A1 aBagshawe A00aUse of phenolic glycolipid 1 for serodiagnosis of leprosy in a high prevalence village in Papua New Guinea. a1030-20 v813 a

This study reports on the usefulness of an IgM phenolic glycolipid 1 (PGL-1) ELISA for serodiagnosis of leprosy in the first year of a prospective longitudinal community survey in a high (8.8%) prevalence village in Papua New Guinea. The IgM PGL-1 ELISA had limited value as a screening method for detection of new cases. Many normal persons, particularly children, had elevated IgM anti-PGL-1 antibodies, presumably a consequence of early subclinical infection.

 a0035-9203