01321nas a2200277 4500000000100000008004100001260001700042653002600059653001100085653002800096653001200124653002400136653002100160653001200181100001200193700001800205700001300223700001400236700001300250700001100263245010800274300001100382490000600393520063000399022001401029 1987 d c1987 Jul-Sep10aAntibodies, Bacterial10aHumans10aImmunoenzyme Techniques10aleprosy10aMycobacterium bovis10aReference Values10aSenegal1 aAgius G1 aBaillargeau E1 aRanger S1 aCastets M1 aMillan J1 aSamb A00a[Anti-BCG antibody titers in healthy and leprous Africans. Value of an indirect immunoperoxidase test]. a209-180 v53 a
An immunoperoxidase reaction was used for the titration of immunoglobulins G and M antibodies to BCG in 171 leprosy patients from Dakar. The results show mean titers decreasing from lepromatous to tuberculoid cases. The antibody profiles of some clinical forms such as reverse reactions, erythema nodosum leprosum are discussed. This test associated to the Mitsuda reaction, bacteriology and histology should allow an easier classification of the borderline forms. The main advantages of the technique are simplicity, speed, low cost and the easy availability of the BCG. These qualities are essential in endemic zone.
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