01122nas a2200193 4500000000100000008004100001260001700042653001100059653001100070653001200081100001500093700001700108700001500125245005200140300001100192490000600203520070500209022001400914 1987 d c1987 Apr-Jun10aBiopsy10aHumans10aleprosy1 aSehgal V N1 aSrivastava G1 aBeohar P C00aHistoid leprosy--a histopathological reapparel. a125-310 v53 a

Twenty three clinically diagnosed histoid leprosy patients were subjected to histopathological and histochemical investigations. The histopathological features were comprise of a well-formed lesion surrounded by a pseudocapsule. In addition, a free, midly eosinophilic, uninvolved sub-epidermal zone, and variously arranged spindle-shaped histiocytes were noted in the lesion. Polygonal and foamy histiocytes were also sited in a few sections. The lesion also had a large number of solid staining acid-fast lepra bacilli. The latter might have stimulated a peculiar histiocytic tissue response almost identical to that seen in histiocytoma(cutis) but for the absence of haemosidrin and lipids.

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