01377nas a2200289 4500000000100000008004100001260001300042653001900055653001100074653002100085653002100106653002100127653002000148653001200168653001200180100001500192700001100207700001700218700001400235700001500249245008500264856004100349300001100390490000700401520066500408022001401073 1985 d c1985 Jun10aAutoantibodies10aHumans10aImmunoglobulin A10aImmunoglobulin G10aImmunoglobulin M10aImmunoglobulins10aleprosy10aVietnam1 aWright E P1 aVlug A1 aGeertzen H G1 aHoang T L1 aNguyen D H00aSerum immunoglobulins, including IgG subclasses, in Vietnamese leprosy patients. uhttp://ila.ilsl.br/pdfs/v53n2a07.pdf a225-320 v533 a

Levels of serum immunoglobulins were measured in healthy Vietnamese and in leprosy patients. Healthy Vietnamese had higher levels of IgG, IgA, IgM, and IgE than did healthy Dutch controls, as well as higher levels of three of the four subclasses of IgG (IgG1, IgG2, IgG3). Lepromatous leprosy patients had significant increases in all classes and subclasses of immunoglobulins, except for IgG2, in comparison with local controls. Tuberculoid leprosy patients had more IgG1, IgG3, and IgG4 than did local controls and had higher total IgG levels. The patients had no increase in autoantibodies against tissue antigens compared to local or Dutch controls.

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