01180nas a2200313   4500000000100000008004100001260001300042653001800055653001800073653002600091653001400117653001100131653001200142653002500154653001200179653001500191653001600206653000900222653001700231100001300248700001400261700001200275700001300287245005400300300001100354490000700365520048000372022001400852       1987                            d  c1987 Nov10aCell Survival10aCrohn Disease10aForeign-Body Reaction10aGranuloma10aHumans10aleprosy10aMicroscopy, Electron10aMitosis10aPhagocytes10aSarcoidosis10aSkin10aTuberculosis1 aCree I A1 aNurbhai S1 aMilne G1 aBeck J S00aCell death in granulomata: the role of apoptosis.  a1314-90 v403 a<p>Unequivocal apoptosis were seen by light microscopy in examples of leprosy, sarcoidosis, tuberculosis, Crohn's disease and foreign body granulomata. A limited electron microscopic investigation showed typical apoptotic bodies in both sarcoid and leprosy granulomata. The number of apoptosis and mitoses in granulomata were counted and their densities calculated. The wide variation in the results between individual lesions may reflect differences in disease activity.</p>  a0021-9746