01199nas a2200241 4500000000100000008004100001260001700042653001200059653001100071653001200082653000900094653002400103653002200127653001300149100001500162700001600177700001500193245008800208300001100296490000600307520063000313022001400943 1986 d c1986 Oct-Dec10aDapsone10aHumans10aleprosy10aMali10aProspective Studies10aRandom Allocation10aRifampin1 aHusser J A1 aBaquillon G1 aPattyn S R00a[Comparison of 3 therapeutic regimens in paucibacillary leprosy. Preliminary note]. a447-520 v43 a
Between 1980 et 1983 all PB patients presenting at the Institut Marchoux, Bamako, took part in a prospective randomized therapeutic trial and were allocated to one of the following regimens: DDS 100 mg 7/7 3 years, RMP 900 mg 1/7 8 doses, RMP 900 mg 7/7 12 doses. At this moment 24, 29 and 22 patients respectively have been followed for periods of 24 to 56 months. With the exception of some irregular drug intake in the DDS patients followed either by relapse or delay in improvement, the efficacity as judged by histopathological examinations did not reveal any difference between the regimens. The study continues.
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