01595nas a2200205   4500000000100000008004100001260001300042653000900055653001900064653001100083653002500094653002900119653000900148653000900157245007100166300001000237490000700247520112100254022001401375       1988                            d  c1988 Dec10aAged10aCryptococcosis10aHumans10aLeprosy, lepromatous10aLung Diseases, Parasitic10aMale10aSkin00a[Virchowian Hansen's disease, Lucio's phenomenon, cryptococcosis].  a47-560 v133 a<p>A 75 years old white male, for 3 years on treatment for virchowian hanseniasis, was admitted with active HD lesions, infiltration on the base of right lung, leg ulcer and malaise. After two days he developed purpura and hemorrhagic blisters in the limbs. The biopsy of these lesions revealed Lucio phenomenon. The patient worsened with mental confusion, psychomotor agitation and anisocoric pupils. In the 18th day of internation the patient died. Necropsy revealed virchowian infiltration plenty of bacilli in the skin and viscera as well as tuberculoid granuloma with acid-fast bacilli in the liver, spleen and bone marrow. These findings lead us to review the patient's classification from virchowian to borderline. In the lungs, leptomeninge, renal papile, prostate and thyroid it was found loose tuberculoid granuloma with a great amount of fungi surrounded by a gelly halo resembling Criptococcus neoformans. These findings and the onset of Lucio phenomenon are discussed in a patient that has been treated for 3 years and still having several virchowian lesions and a great amount of acid-fast bacilli.</p>  a0100-3283