01187nas a2200253   4500000000100000008004100001260001300042653002500055653001200080653001600092653002900108653001200137653001500149653000900164653002500173100001600198700002100214700001500235245005800250300001000308490000700318520059400325022001400919       1977                            d  c1977 May10aAdministration, Oral10aAnimals10aBCG Vaccine10aInjections, Subcutaneous10aleprosy10aLevamisole10aMice10aMycobacterium leprae1 aShepard C C1 aVan Landingham R1 aWalker L L00aEffect of levamisole on Mycobacterium leprae in mice.  a564-70 v163 a<p>Levamisole, an antihelminthic drug that is capable of enhancing immune responses in mice and in humans, was tested in experimental Mycobacterium leprae infections in mice by a number of schedules. Intermittent schedules were used, and administration of the drug was started (i) around the time of inoculation with M. leprae, (ii) when the M. leprae population was approaching the plateau level, (iii) after the onset of the plateau phase, or (iv) after BCG vaccination 28 days following the inoculation with M. leprae. No effect of drug could be discerned with any of the schedules.</p>  a0019-9567