01333nas a2200253 4500000000100000008004100001260001300042653001000055653001100065653001100076653001200087653000900099653001600108653000900124100001300133700001500146700001400161245004200175300001100217490000700228050003200235520079800267022001401065 1988 d c1988 Oct10aAdult10aFemale10aHumans10aleprosy10aMale10aMiddle Aged10aZinc1 aSaxena N1 aSharma R P1 aSingh V S00aStudy of serum zinc level in leprosy. a556-610 v60 aInfolep Library - available3 a

Serum Zinc level was estimated in different types of leprosy by 'Dithiazone extraction' method in 75 leprosy patients comprising 15 each of Tuberculoid-Tuberculoid (TT); Borderline Tuberculoid (BT); Borderline Borderline (BB); Borderline Lepromatous (BL) and Lepromatous Lepromatous (LL). These findings were evaluated in comparison to 15 normal subjects serving as controls. Serum zinc level was observed to be significantly low in all types of leprosy except tuberculoid leprosy (TT). No significant difference was observed in serum zinc levels before and after 90 days of dapsone Therapy. The findings of our study are of considerable importance as zinc deficiency can be one of the factors involved in non-specific suppression of cell mediated Immunity (CMI) in lepromatous leprosy.

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