01259nas a2200265 4500000000100000008004100001260001300042653001500055653004600070653001400116653001100130653002000141653002200161653001200183653000900195100001800204700001400222700001600236700002100252245007900273300001200352490000700364520060800371022001400979 1988 d c1988 Dec10aAdolescent10aGlomerulonephritis, Membranoproliferative10aGranuloma10aHumans10aKidney Diseases10aKidney Glomerulus10aleprosy10aMale1 aAl-Mohaya S A1 aCoode P E1 aAlkhder A A1 aAl-Suhaibani M O00aRenal granuloma and mesangial proliferative glomerulonephritis in leprosy. a599-6020 v563 a

A 17-year-old, Yemeni male patient with borderline lepromatous leprosy and erythema nodosum leprosum (ENL) developed a nephritic range proteinuria. A renal biopsy revealed mesangial proliferative glomerulonephritis and epithelioid granulomas in the interstitium. The presence of granular immunofluorescence for C3 and electron-dense deposits in the glomeruli indicated an immune complex glomerulonephritis. Clinical signs of ENL subsided rapidly under steroid treatment. The unusual combination of proliferative glomerulonephritis and epithelioid granulomas in leprosy is presented and discussed.

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