01156nas a2200241   4500000000100000008004100001260001300042653001200055653002300067653001600090653003000106653001200136653000900148653001800157653002600175100001600201245009000217300001000307490000700317050003200324520054400356022001400900       1988                            d  c1988 Apr10aAnimals10aBacterial Vaccines10aBCG Vaccine10aHypersensitivity, Delayed10aleprosy10aMice10aMycobacterium10aVaccines, Inactivated1 aDesikan K V00aEvaluation of the efficacy of candidate vaccines against M. leprae infection in mice.  a252-90 v60  aInfolep Library - available3 a<p>Delayed-typed hypersensitivity (DTH) response and protection value of some of the candidate vaccines alone and in combination with BCG has been investigated. It was observed that both M.w. and BCG gave heightened DTH and good protection. On the other hand both M. leprae and ICRC evoked moderate DTH and gave poor protection. However on combining any of these candidate vaccines with live BCG, the lowering of DTH and poor protection was observed except in the M. leprae combination which in spite of low DTH gave better protection.</p>  a0254-9395