01387nas a2200229 4500000000100000008004100001260001300042653002600055653002400081653003500105653001200140653002500152100001300177700001400190700001400204245013300218300001000351490000700361050003200368520074300400022001401143 1988 d c1988 Oct10aAntibodies, Bacterial10aAntigens, Bacterial10aFluorescent Antibody Technique10aleprosy10aMycobacterium leprae1 aRana N S1 aGupta H P1 aSingh N B00aUse of non-conventional antigen: M. habana in detecting M. leprae antibodies from leprosy patients and contacts in FLA-ABS test. a593-90 v60 aInfolep Library - available3 a

An indirect immunofluorescent (FLA-ABS) test has been developed to detect M. leprae specific antibodies in the active and subclinical cases of leprosy. An antigenically related mycobacterium, M. habana, was used as an antigen to detect M. leprae specific antibodies in the sera samples of leprosy patients. A comparison was made with M. leprae antigen using same set of sera samples. M. habana is capable of detecting anti-M. leprae antibodies in the serum samples of leprosy patients, previously absorbed with various mycobacterial antigens, cardiolipin and lecithin, almost to the same percentage as M. leprae. Possible use of M. habana antigen as an alternative to M. leprae, in the serodiagnosis of leprosy, has been discussed.

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